The
main objectives of the Department of Oncology-Pathology are basic,
translational and clinical research and educational activities related
to cancer. Approximately 300 people from over 40 nations are currently
working at the department. 37 research groups with various cancer
research profiles are involved and we have around 120 PhD students. The
Department of Oncology-Pathology is responsible for undergraduate
courses in Pathology, Oncology and Forensic Medicine for medical
students, as well as for Tumor biology courses for biomedicine students
and Pathology courses for opticians.
Description of research group and projectDepartment
of Oncology-Pathology is looking for a student who wants to work with
Prof. Dan Grandér, docent Katja Pokrovskaja Tamm and co-workers to
study the role of autophagy in anti-cancer therapy. The exact mechanism
by which chemo-therapeutic drugs kill cancer cells is still not fully
understood. Many drugs induce autophagy, a cellular response to
starvation and stress, and its role in drug-induced cell death is
controversial. The goal is in a high throughput manner to determine how
autophagy is involved in response to cancer treatment and cancer cell
survival. In addition, we want to characterize and validate novel
compounds that inhibit autophagy and reveal the molecular mechanisms of
drug-induced autophagy. The overall aim of our research is to improve
performance of anti-cancer drugs and create novel treatments for
personalized and targeted cancer therapy.
Duties and responsibilitiesThe PhD student will be responsible for the planning, experimental work, data analysis and presentation in a close collaboration with both the group members and with our external collaborators such as the Chemical Biology Consortium at KI (LCBKI) and the Biotech Company Sprint Bioscience. The project will include advanced cell and molecular biology, high throughput screening, autophagy studies, gene delivery, flow cytometry and high-throughput microscopy.
Entry requirements
To meet the general entry requirements for doctoral studies, an applicant must have
1. taken a Master's degree
2. completed course requirements for at least 240 higher education credits, including at least 60 second-cycle higher education credits, or
3. otherwise acquired essentially the same knowledge in or outside Sweden.
An applicant who met the general entry requirements for third-cycle studies before 1 July 2007 is regarded as having met the current requirements, though no longer than until the end of June 2015.
Applications are welcome from talented students, preferably with experience in cytotoxic drug screening/assays, molecular biology of cancer and programmed cell death. Candidates should have at least 6 months of experience in practical laboratory work. Excellent ability to express themselves in speech and writing in English is a requirement. We are seeking a highly motivated and creative person. The candidate should have good communication skills and the ability to interact effectively and work productively in a team. Emphasis will be placed on personal skills, knowledge and abilities, and on previous experience in experimental work. A decision concerning the doctoral student position will be made after the initial trial period and after a successful admission seminar (see below).
A selection will be made among qualified applicants on the basis of the ability to benefit from doctoral studies. Karolinska Institutet uses the following bases of assessment:
- Documented subject knowledge of relevance to the area of research
- Analytical skills
- Other documented knowledge or experience that may be relevant to doctoral studies in the subject
The qualifications of the applicants will be evaluated on an overall basis.
The vacancy (PhD position) will be filled on condition that the successful applicant is admitted to doctoral education. An overall assessment of the applicants’ qualifications will be made. . For additional information about doctoral studies at Karolinska Institutet, see http://www.ki.se/doctoral
NotesFor the first two years the student is awarded doctoral student allowance (not employment) that after half-time review will be transformed into a paid position as a PhD student employment.
The PhD studies at full time are maximum 4 years. Requirements for graduate students are contained in the Higher Education Chapter 5,§1-7.
Application process
An application must contain the following documents in Swedish or English:
The application is to be submitted on the NetRecruiter system.
Duties and responsibilitiesThe PhD student will be responsible for the planning, experimental work, data analysis and presentation in a close collaboration with both the group members and with our external collaborators such as the Chemical Biology Consortium at KI (LCBKI) and the Biotech Company Sprint Bioscience. The project will include advanced cell and molecular biology, high throughput screening, autophagy studies, gene delivery, flow cytometry and high-throughput microscopy.
Entry requirements
To meet the general entry requirements for doctoral studies, an applicant must have
1. taken a Master's degree
2. completed course requirements for at least 240 higher education credits, including at least 60 second-cycle higher education credits, or
3. otherwise acquired essentially the same knowledge in or outside Sweden.
An applicant who met the general entry requirements for third-cycle studies before 1 July 2007 is regarded as having met the current requirements, though no longer than until the end of June 2015.
Applications are welcome from talented students, preferably with experience in cytotoxic drug screening/assays, molecular biology of cancer and programmed cell death. Candidates should have at least 6 months of experience in practical laboratory work. Excellent ability to express themselves in speech and writing in English is a requirement. We are seeking a highly motivated and creative person. The candidate should have good communication skills and the ability to interact effectively and work productively in a team. Emphasis will be placed on personal skills, knowledge and abilities, and on previous experience in experimental work. A decision concerning the doctoral student position will be made after the initial trial period and after a successful admission seminar (see below).
A selection will be made among qualified applicants on the basis of the ability to benefit from doctoral studies. Karolinska Institutet uses the following bases of assessment:
- Documented subject knowledge of relevance to the area of research
- Analytical skills
- Other documented knowledge or experience that may be relevant to doctoral studies in the subject
The qualifications of the applicants will be evaluated on an overall basis.
The vacancy (PhD position) will be filled on condition that the successful applicant is admitted to doctoral education. An overall assessment of the applicants’ qualifications will be made. . For additional information about doctoral studies at Karolinska Institutet, see http://www.ki.se/doctoral
NotesFor the first two years the student is awarded doctoral student allowance (not employment) that after half-time review will be transformed into a paid position as a PhD student employment.
The PhD studies at full time are maximum 4 years. Requirements for graduate students are contained in the Higher Education Chapter 5,§1-7.
Application process
An application must contain the following documents in Swedish or English:
- A personal letter and curriculum vitae
- A copy of a degree certificate and associated certificates
- A copy of a degree project and any previous publications
The application is to be submitted on the NetRecruiter system.
Karolinska Institutet is one of the world´s leading medical
universities. Its mission is to contribute to the improvement of human health through research and education. Karolinska Institutet accounts for over 40 per cent of the medical academic research conducted in Sweden and offers the country´s broadest range of education in medicine and health sciences. Since 1901 the Nobel Assembly at Karolinska Institutet has selected the Nobel laureates in Physiology or Medicine.Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.
universities. Its mission is to contribute to the improvement of human health through research and education. Karolinska Institutet accounts for over 40 per cent of the medical academic research conducted in Sweden and offers the country´s broadest range of education in medicine and health sciences. Since 1901 the Nobel Assembly at Karolinska Institutet has selected the Nobel laureates in Physiology or Medicine.Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.
Application Deadline : 11 March 2013
